Side effects associated with the use of intravascular iodinated contrast media are usually transient and are classified as light or moderate, although the observed severe, life-threatening reactions, including fatal.
When intravascular administration of a contrast agent most commonly observed: nausea, vomiting, skin redness, heat sensation. Reducing exemestane bodybuilding hot flashes and nausea can be achieved if a contrast agent is injected slowly or take short breaks (every 3-5 minutes) during administration.
It is also possible to develop the following symptoms: chills, fever, sweating, headache, dizziness, pale skin, weakness, gagging and a feeling of breathlessness, wheezing, sneezing, watery eyes, increase or decrease in blood pressure, itching, hives, swelling, convulsions, muscle tremors. It is possible that the occurrence of such side effects may be a harbinger of incipient anaphylactic shock. In case of shock, the introduction of contrast medium must be stopped immediately and assign the appropriate intravenous therapy if necessary. Allergic and anaphylactoid reactions may occur regardless of the amount and manner of administration of the contrast agent. Giperergicheskim reactions occur more frequently in patients predisposed to allergies.
Severe adverse reactions requiring emergency treatment can occur in the form of circulatory disorders, which are expressed in the expansion of peripheral blood vessels and the subsequent lowering of blood pressure, reflex tachycardia, dyspnea, cyanosis, restlessness, confusion, until he lost consciousness. In this regard, in a study with the purpose of providing emergency assistance must be ready appropriate medicines, endotracheal tube and ventilator.
In a few cases, mainly in patients exemestane bodybuilding suffering from epilepsy or brain diseases may develop neurological complications, such as coma, disorientation, drowsiness, temporary paresis, impaired vision, as well as epilepsy.
In some cases, the application of the drug may develop phlebitis, thrombosis. In rare cases, reversible renal failure may occur.
In case of accidental overdose or a significantly reduced renal function, the drug may be removed from the body by extracorporeal dialysis.
Interaction with other drugs
should be borne in mind that the iodine-containing contrast agent reduces the ability of the thyroid tissue to accumulate drugs radioisotope diagnostic tests for more than two weeks.
In patients suffering from diabetic nephropathy and receiving biguanides, with the introduction of a contrast agent may develop lactic acidosis. To prevent this complication should stop taking biguanide for 48 hours before the procedure. To resume receiving biguanides should ensure there are no violations of kidney function.
Hypersensitivity reactions can be more pronounced in patients taking beta-blockers.
In patients taking interleukin, more likely to have delayed reactions exemestane bodybuilding (eg, fever, rash, itching, joint pain) and flu-like symptoms.
when storing the drug may loss crystal. In such cases, the vial should be heated in a water bath (temperature about 60 ° C), shaking occasionally. If the crystals disappear and upon cooling to 33 – 37 ° C they do not fall out again, and the solution is usable.
Impact on management vehicles and machinery
In rare cases, it is possible to slow down the reaction that may interfere with the ability of driving vehicles and work with other mechanisms.
Solution for injection 60%, 76%
In 20 ml amber glass vial (type 1) with a notch.
- 5 ampoules in a cardboard bezgyachakova contour package complete with ampoule knife and instructions for use are placed in a cardboard box.
- 5 vials complete with ampoule knife and instructions for use in the cold exemestane bodybuilding. 1 cold box placed in a cardboard box.